Old Moncks Corner stood near the intersection of Highway 17A and Highway 52, but it was abandoned in 1856 when the North-Eastern Railroad was routed from Charleston to Bonneau. A railroad depot was placed at the northwest corner of Main Street, formerly Pinopolis Road, and the tracks, and New Moncks Corner grew around that intersection and its scheduled train stop. As business increased, a new railroad station with a depot and waiting rooms for passengers was built across the tracks at the northeast corner of the intersection. In 1902, that depot and station was moved to the southwest corner of the intersection, where it remained. The depot gave Berkeley County farmers and lumbermen a way to send their products to market and allowed homeowners and businesses to receive mail, supplies, and catalog items. After World War Two, rail travel and freight shipping declined as the highway system improved, and trains stopped using the depot in 1975. Moncks Corner officials prevented it from falling into ruin, and after a complete renovation in 2000 it was preserved as an important landmark. It now serves as the town’s Visitor and Cultural Center, hosting special events and classes, offering a gift shop, and once again functioning as a commercial and social center for Moncks Corner.