The Rev. William H. Travis formed a school and Missionary Baptist Church in Palacios in 1905, and that year the congregation became known as First Baptist Church. In 1906, the Texas Baptist Convention chose Palacios as the site for its Baptist Training Union Encampment, bringing missionaries and teachers into the community each year. At the corner of Welch and Second Street in 1909, the church built a sanctuary after having worshiped previously in homes and at the encampment tabernacle. The congregation grew over the next decades, moving in the 1970s to a larger building at this site, where it has continued to grow and serve its community.