Brady's Bluff Prairie State Natural Area is a protected prairie bluff in western Wisconsin within Perrot State Park, rising more than 450 feet above the Mississippi River near Trempealeau. Its sandstone base and Prairie du Chien dolomite cap create a dry, exposed slope that supports an unusually rich bluff prairie community. More than 100 prairie plant species have been recorded there, including several near the northeastern edge of their range and others considered rare. The site also provides habitat for rare butterflies and the state-threatened wing snaggletooth land snail, making it an important surviving remnant of the upper Mississippi River bluff prairies and a significant conservation area.