The Rev. Hugh Wilson organized Prospect Presbyterian Church at this site in February 1839 on land included in a Mexican land grant to James F. and Emily Perry, making it the second Presbyterian church founded in Texas. Worship services were held in a log schoolhouse, where in 1840 the first Presbytery of Texas, Brazos, was organized. The congregation's second pastor, the Rev. James Weston Miller, founded Live Oak Female Seminary in 1853, and the church building housed some school classes. Under Miller's direction, a foundation was laid here for a new sanctuary before the Civil War, and those unused foundation stones still remain. A new building was erected south of here near the seminary in 1872. The church disbanded in 1928, and its members transferred to Brenham Presbyterian Church, while the 1872 building was dismantled in 1956. Oak Rest Cemetery contains many pioneer members of Prospect Presbyterian Church, including the Miller family, as well as veterans of the Texas Revolution and the Civil War, and together with the nearby site of the Live Oak Female Seminary and the church foundation stones, it reflects the area's pioneer heritage.