Joshua James, accompanied by members of his family, arrived by flatboat five miles south of here at Lamb's Ferry in 1820. Reverend James was an itinerant minister sponsored by the Baptist Church of Boston, Massachusetts. Their home, located north of the ferry, served as an early place of worship, as well as a schoolhouse. The teacher was Joshua's 15-year-old daughter-in-law, Esther James. While away on a preaching mission, their log cabin was destroyed by fire. The James family then moved to Rodgersville, the original spelling, where the only organized religious function at that time was a brush arbor service at Liberty Cemetery. This concern was shared with the Boston Baptist Church. On October 15, 1841, for one dollar, a one-acre lot located approximately 175 yards east of this location was deeded to trustees Washington Gilbert and Joshua Stamps on behalf of the United Baptist Church of Jesus Christ. The town's first completely wood-framed church building was constructed there the following year, and the town's first schoolhouse was located beside the church. Joshua James Jr. and Esther's daughter, Sarah, Sallie, became a teacher in 1845. Joshua James died on an unknown date and is believed to be buried in an unmarked grave in Liberty Cemetery. Beginning circa 1865, the Baptist Church building accommodated Methodist, Presbyterian, and Church of Christ congregations for approximately 25 years. In August 1905, Lauderdale County Missionary of the Baptist Mission Board Reverend R. E. Paulk assisted Reverend R. H. Tandy with an on-site tent revival. The small wooden building was demolished, and a one-room frame structure was built at the same location. In 1906, the Rogersville Baptist Church organized, joining the Lauderdale County Baptist Association. In 1947, the church building was again replaced, this time with a westward-facing building. The First Baptist Church of Rogersville was incorporated on July 6, 1958. Upon the advice of the Baptist Sunday School Board in Nashville, Tennessee, the congregation purchased a larger tract of property at this location. Meetings were held in the basement until Easter Sunday of 1960, when the first service was held in the more modern building. For 12 years, classes for youth met in the Warmack home place, which was located across the street from the sanctuary. The first service in the current sanctuary was held on October 18, 1992. There is no known recorded list of all ordained Baptist ministers who served the church during its first 90 years, but 17 men pastored the church from 1931 through 2021.