Jamesville Primitive Baptist Church is a rectangular building with the classic two-front-door entrance common in Primitive Baptist churches, with one door for men and one for women, and with the plain form typical of the region. Its large boxed cornices, deep frieze returning to frame the front gable, and other features such as louvered gable vents reflect Greek Revival design popular in the antebellum period, and it once had nine-over-six sash windows. The congregation began in 1827 when about fifty members of Skewarkey Baptist Church left to form a new congregation called Picot about halfway between Williamston and Jamesville. Young Clayton Moore, later a wealthy planter, was influenced by the church, became licensed to preach, and served as its pastor from 1847 until his death in 1881. A strong supporter of the Confederacy, Moore saw his plantation house burned by Union troops during the war. Afterward, being rich in land but poor in cash, he arranged for the congregation to give him the church building, presumably as a temporary dwelling, in return for his promise to build a new church in Jamesville. By 1870 the congregation occupied this new structure and took the name Jamesville Primitive Baptist Church. Over the years membership and activities declined, and in 1953 Luther Hardinson, the last surviving member and deacon, deeded the property to the Jamesville women’s Club, which adapted the building with partitions, a kitchen, and bathrooms while retaining some of the original pews for seating. The building continues in use by the Women’s Club.