A school building was built here in 1852 on public lot #73, which had originally been designated for a paupery. Mary Fuller Frazier attended this school in 1881. Perryopolis's first school was established in 1820 in the Old State Bank Building. In 1828, a schoolhouse was erected on public lot #69, a triangular lot to the rear of the First Christian Church, but that building is no longer standing.