Old Main was constructed in 1905 by workers of the Gospel Trumpet Company to provide housing for their families. Timbers came from the St. Louis World's Fair. Building blocks were made by hand on the site. It became the birthplace of Anderson College in 1917, providing offices, classrooms, laboratories, living quarters for faculty and students, a chapel, library, laundry, dining room, and post office. It was replaced by Decker Hall in 1970.