Originally constructed by Daniel Washington Biggs and his business partner in the late 1880s, the house served for several years as a boarding house for northern lumber buyers visiting their large local sawmill. After Dr. Henry Edwards and his wife, Caroline "Carrie" Haselden Edwards, purchased it, it became the first two-storied house in Latta and the family home where Dr. and Mrs. Edwards raised their children. The interior has been restored to reflect the décor of their time there, and the home became a gathering place for the extended Edwards and Haselden families, enjoyed by both sides of the Edwards family. For his medical practice, Dr. Edwards had his office built next door, in the building that is now the Dillon County Museum. The town of Latta later bought the house from the Dillon County Historical Society for $1 to save it from demolition, and the Latta Revitalization Commission restored it for use in functions and as space for two offices, while members of the Friends of the Edwards House support its upkeep and continued improvement.