East End High School was the first school for African-American students in eastern Lauderdale County. Before it opened, several elementary schools for African-American children served the area, including Rogersville School on the north side of Lee Highway just east of First Creek, while junior high and high school students were bused to Burrell High School in Florence. In early 1946, the Lauderdale County Board of Education received $25,000 from the state of Alabama's Building Commission Fund to replace Little Zion School, located 1.5 miles southeast of here, after fire damage. In 1951, land just south of the Rogersville town limits on the south side of Lovers Lane and west of Lamb's Ferry Road was purchased from Margaret King Fuqua and the late Slim Fuqua Sr., and East End High School was built there. The school opened in 1952 for grades 1 through 12 with William M. Ford as principal. An auditorium-gymnasium was dedicated on May 3, 1953, with Psalm 84:1-12 as the dedication scripture, and a lunchroom opened in 1954, serving 178 students in all grades. The first graduating class, in the 1953-54 school year, consisted of two female students. In May 1961, the Lauderdale County Board of Education adopted a plan to consolidate all schools for African-American students into two schools, using Old Jackson Highway through St. Florian as the dividing line; under this plan, Hewitt and Killen, with 17 students each, and Center Star, with 53 students, were sent to East End High School. Before consolidation, East End had teachers and 84 students in elementary school, 55 in junior high, and 44 in high school, and additional classrooms were built to accommodate increased enrollment. The first homecoming activities took place on Saturday, February 3, 1962. On April 23, 1965, the Lauderdale County Board of Education and Superintendent fallen Thronton adopted a plan to begin integrating all grades in the Lauderdale County system with the 1965-66 school year. Seven former East End High School students were members of the 1966 Lauderdale County High School at LCHS for the 1966-67 school year. When East End High School officially closed in 1967, 88 students were attending all 12 grades. The 17-acre campus and building were sold two years after its closing, and all remaining buildings were demolished in 2016.