In the first decade of the 20th century, Hispanics from central Texas, Mexico, and nearby ranches settled in the newly founded town of San Benito, including families who followed the principles of the Presbyterian Church of Mexico. By 1909, these families had organized a Spanish-speaking congregation that met in homes for worship, and in 1911 Presbyterian families in San Benito organized the Mexican Presbyterian Church of San Benito. Anne E. Dysart, a missionary and teacher who evacuated Mexico during that country's revolution, led services and opened a school, and the congregation officially dedicated the church on October 19, 1911. By 1912, the congregation had gathered funds to purchase a lot at the corner of Biddle and Hull Streets for its first church building. The church reorganized in 1917, became a member of the Presbyterian Church of the U.S.A. in 1919, and that year moved its buildings to 140 Diaz Street. As the congregation became predominantly English-speaking, the church changed its name to 2nd Presbyterian Church in 1961, and in 1979 members renamed it Getsemani Presbyterian Church. Over many years, the congregation aided the community by hosting the Texas Migrant Council's Community Center, running a food bank and clothes closet, functioning as an emergency distribution center, offering English classes, and establishing a benevolent fund for the indigent. It also pursued outreach by opening missions in Harlingen, Las Flores, and El Fresnal and conducting mission work in Mexico, and it continues to serve as a spiritual leader in the San Benito community.