La Plata is a city in Macon County, Missouri, United States. The population was 1,257 at the 2020 census, down from 1,366 in 2010. La Plata is located next to the Adair County line and is on a mainline of the BNSF Railway. The town is best known for La Plata station, which provides passenger rail service to Chicago and Los Angeles.

Hear every story as you drive

4.8 Stars · 800+ Ratings