Penns Grove is a borough in Salem County, in the U.S. state of New Jersey. As of the 2020 United States census, the borough's population was 4,837, a decrease of 310 (−6.0%) from the 2010 census count of 5,147, which in turn reflected an increase of 261 (+5.3%) from the 4,886 counted in the 2000 census.

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