CITY · 21 STOPS

Wyatt, Missouri

Wyatt is a city in Mississippi County, Missouri, United States. The population was 219 at the 2020 census, down from 319 in 2010. It is the easternmost city west of the Mississippi River.

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Things to see

TRANSPORTATIONGreat River Road Illinois

HISTORYThe Beginning of the Third Principal Meridian

HISTORYCritical River Confluence

HISTORYLewis & Clark

MILITARYFort Defiance

SCIENCE & TECHThe Ohio River Bridge

MILITARYCairo, Illinois

HISTORYHistorical Survey Marker

MILITARYMary J. Safford

HISTORYCairo Connection

MILITARYAfrican American Troops in the Civil War

FAITHThe Historic First Presbyterian Church

Nearby places

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