Medgar and Myrlie Evers House possesses national significance as the home of Medgar and Myrlie Evers, both important participants in the Civil Rights movement. As Field Secretary for the National Association for the Advancement of Colored People, Medgar Evers was at the forefront of every major civil rights event in Mississippi from 1955 until his assassination in 1963. His assassination in the house's carport forced Myrlie Evers into a more prominent role in the civil rights movement.