Situated at the intersection of major roads, a railroad, and a canal, Millerstown flourished in the 19th and 20th centuries. Stage coaches, horse-drawn wagons and carriages gave way to automobiles by 1913, when some Millerstown residents owned their first cars. As early as 1915, Charles E. Rippman sold and serviced automobiles and motorcycles on North Market Street. In 1921, J. D. and Roy Cupp operated Cupp Brothers Auto Supplies and Repairs on Locust Street. In 1936, J. D. relocated the company to North Market Street and acquired a Chrysler-Plymouth agency. Edwin Lash and Samuel Potter bought the business in 1976 and, and in 1978 Potter became sole owner. J.P. Russell & Son established a fuel oil business in 1939 along Locust Street. They hauled the fuel to customers in a tank on the back of a pickup truck from which it was unloaded manually into five-gallon buckets, hand-carried and dumped into 55-gallon drums. In 1964, they moved to 60 North Market Street, where they operate in 2019. They now have several delivery trucks and a tractor-trailer. H. F. Campbell, "Pop" and Sons began their trucking business in 1933 with a Ford stake-body truck. Later "Pop" added three Ford dump trucks which were used to build the Pennsylvania Turnpike. In 1940, son Bob Campbell hauled stone from Binkley Quarry, Dry Run to help build to Bethlehem Steel Company. AFter his service as a Marine in World War II, Bob left the trucking company. "Pop" and son Ben continued the operation for many years. At its peak, the company ran 70 tractors and 230 trailers with 90 employees. When Ben's sons joined the business, the company evolved into Camel Express which operated through 2013, 80 years of service to the community. Today, locals travel outside of the area for most of their daily needs. However, the square remains a major intersection for businesses, residents, farmers and truckers attending to their daily business.