Miltonville, along the banks of Elk Creek, was platted in 1816 by George Bennett, Theophilus Eaglesfield, and Richard V. V. Crane. Elk Creek served two grist mills, one built around 1804 and operated by a free black, Bambo Harris, and a second built by George Bennett in 1815. An Indian burial ground stood on the east bank of Elk Creek near the site of Huff's Ferry. Eagle Tavern, the area's first three-story brick inn, served as a stopover for stagecoach lines traveling the Miltonville-Trenton Turnpike. The village became known for pottery factories, vineyards and wineries, and Frisch's brickyard, established in 1880. The United Brethren Church, organized in 1811, and Miltonville Cemetery hosted church conferences and celebrations. Miltonville School operated from the 1800s to 1936, and the local post office was in service from 1889 to 1904.