This one-story Greek Revival-style house was constructed about 1847 with a wood façade shaped to resemble stone blocks and a hexagon-shaped entrance vestibule. On October 5, 1863, Confederate Major Amos McLemore, who had been sent to the area to round up deserters, was shot and killed in the house by Newton Knight. The Amos Deason home was listed in the National Register of Historic Places in 1984 and designated a Mississippi Landmark in 2000.