The Civil War on the Missouri-Kansas border grew out of the raiding and looting of the Bleeding Kansas era from 1854 to 1860, as Kansas Jayhawkers and Redlegs in Union blue looted and burned Missouri towns and farms, and guerrillas known as bushwackers rose to harass Federals, defend local interests, and support the Southern cause. Neither side gave quarter, prisoners were shot on sight, and revenge spread across the region as families were terrorized and property stolen. In the summer of 1863, after relatives of guerrillas were imprisoned in Kansas City and a prison collapsed in August, killing four women and crippling several others, William Quantrill led more than 400 men into Lawrence, Kansas, on the morning of August 21, 1863, where they burned and looted the town and killed more than 150 men and boys before escaping back to Missouri. Four days later, Union commander Gen Thomas Ewing issued Order No. 11, requiring nearly all civilians in Jackson, Cass, Bates, and northern Vernon counties to evacuate within 15 days in order to create a neutral zone and reduce violence. Under a sweltering September sun, mostly women, children, and old men left because many fighting-age men were away, and with good horses, wagons, and buggies already stolen by Redlegs, Jayhawkers, Federal soldiers, or bushwackers, many people walked or used small oxen-pulled wagons. As families departed, soldiers burned homes, barns, and outbuildings, while animals and forage were confiscated or stolen, leaving such complete devastation that the region became known as the Burnt District, marked for miles by charred chimneys called Jennison's Tombstones after Col. Charles "Doc" Jennison, who directed much of the wartime destruction. In Cass County, the population fell from nearly 10,000 in 1860, including more than 1,600 families, to only a few hundred people in Harrisonville and Pleasant Hill, and more than 60 percent never returned. The order's human toll was remembered in accounts such as Cole Younger's story of his sick mother Bursheba, who was forced to burn her own buildings, and Caroline Dye's account of fleeing with a neighbor after troops and Jayhawkers took livestock, food, bedding, crops, machinery, and nearly everything of value. After the war, Isaac Percival Dye built a new house around the one room left standing from the Dye home, and Harry Truman lived there with his family from 1885 to 1887.