The 1817 Treaty of Fort Meigs opened much of northwest Ohio to white settlement while granting the Wyandot Nation permanent use of the Grand Reserve at present-day Upper Sandusky. There farming continued, a school was built, and in 1824 this Mission Church was constructed by Indians and Methodist missionaries. The Indian Removal Act of 1830 then called for relocation of all eastern Native Americans to areas beyond the Mississippi River. By 1840 all Ohio Indians had been removed except the Wyandot, who refused to leave and preferred to remain on their Sandusky, now known as Killdeer, Plains. Under considerable pressure from federal authorities, the Wyandot Nation agreed in 1842 to relinquish the Grand Reserve and move west. From this site on July 12, 1843, 664 individuals began a week-long journey to awaiting steamboats at Cincinnati. The Wyandot were the last organized Native American people to leave Ohio, and they settled in modern-day Kansas and Oklahoma.