Built at Eastport and moved to Iuka circa 1860, Twin Magnolias served as Confederate Brigadier General Henry Little's headquarters during the battle of Iuka. Little was killed in the action and buried in the yard of the house, and his body was later moved to Baltimore, Maryland. Twin Magnolias was also the home of John M. Stone's family. A colonel during the Civil War, Stone would later become the state's longest-serving governor and the second president of Mississippi A&M College in Starkville.