Flores Rancho emerged from lands assigned to Mission Espada and Rancho de las Cabras in the early 1700s. Before it had its current name, mission-owned land here was called Chayopines after the Native Americans who once occupied the area. As prime ranching land used to raise cattle, goats, and other livestock to support the mission, the early Chayopines Rancho encompassed 13,284 acres granted by the King of Spain. In the mid-eighteenth century, as Spanish civilian settlement became more important in areas near San Antonio, La Bahia, and east Texas, sites called Parajes were often placed at river crossings where travelers could camp overnight. Juan Jose Flores occupied an adobe house here by 1756 at the river crossing known as El Paraje Nombrado Chayopines. This adobe hacienda is believed to date from Flores' time and is considered the oldest home in Wilson County. In 1844, a brick house was built around the original adobe structure. Several yards north of the hacienda are the ruins of a chapel built in the early 1800s, with only the stone foundation remaining, and the ruins of an associated burial ground, or Campo Santo, lie within the chapel remains. After Juan Jose Flores' death, the rancho passed to his son Pedro and then to his son Francisco. Although portions of Flores Rancho have been sold several times over the past two centuries, the adobe hacienda and chapel site remain as reminders of centuries of Hispanic heritage in the area.