Olompali was the site of the largest known villages of the Coast Miwok. Preliminary archaeological investigations indicate that about 100 acres had been occupied for centuries before the arrival of Spanish explorers and padres. As recently as 1850, the shoreline of San Pablo Bay was near where Highway 101 is now, enabling the Coast Miwok to live from the bounty of both land and sea. The earliest verified contact between Spaniards and the Olompali people came in 1814, when the first Olompalis were baptized at Mission San Francisco de Asis. This began changes that transformed the villagers' lives forever as their numbers dwindled and their lands were occupied by people with very different cultures.