Clark Creek Natural Area is a 700-acre preserve in Wilkinson County, Mississippi, known for steep wooded ravines, about 50 waterfalls, and an unusually varied landscape of hardwood and pine forest on sharply sloping bluffs. Established in 1978 through a partnership of conservation groups, local government, private landowners, and state agencies, it protects notable plant diversity, including world record Mexican plum and bigleaf snowbell and the state record hophornbeam. Its wildlife includes migratory birds, white-tail deer, foxes, bobcats, black bear, snakes, an endangered Southern red belly dace, and a rare land snail. Managed for hiking, bird watching, and conservation, it remains protected from more intensive development.