Cuckoo, long a landmark for travelers, was built for Henry Pendleton about 1819. Nearby once stood the Cuckoo Tavern, from which in 1781 Jack Jouett made his famous ride. The Pendletons, a prominent family of physicians whose descendants still own the house, constructed two doctor's offices at Cuckoo that still stand; one was built in the 18th century and one in the 19th. The house retains many Federal-style details as well as an early-20th-century Colonial Revival portico. Cuckoo was listed on the National Register of Historic Places and the Virginia Landmarks Register in 1994.