A segment of the noted east-west Indian route called the Lower Uchee Path closely coincides with this highway. Beginning at Old Town on the Ogeechee, the trail led by Carr’s Shoals on the Oconee above Dublin, then by way of Cochran, Hawkinsville, and Montezuma to Uchee Town on the Chattahoochee River in Russell County, Alabama. At the Ogeechee, it connected with various paths leading from former Uchee settlements on the middle Savannah River. The route was opened around 1729 when the Uchees began removing to the town on the Chattahoochee River, and it paralleled another trail to the northward known as the Upper Uchee Path.