At the request of Dr. and Mrs. J.C. Maxwell, major benefactors, the orphanage was named in memory of their daughter Constance Pope Maxwell, who died at the age of seven. Connie Maxwell Orphanage, a ministry of the South Carolina Baptist Convention, received the first child in care at the infirmary building on this site on May 22, 1892. Twelve-year-old Susie Burton of Newberry County was the first child received into care there by Miss Rachel Reagan, matron, and by the end of that year twenty-six children were in residence. In 1946, as more dependent children were placed in care, the name was changed to Connie Maxwell Children's Home. Through the beneficence, giving, and leadership of Dr. and Mrs. J.C. Maxwell, and with interest and support from the Greenwood community, this child-care ministry grew over the years and provided hope, healing, care, and nurture to thousands of children and families.