Dana Adobe, or Casa de Dana, is a historic adobe house in Nipomo, California, built as the home of William Goodwin Dana, a Boston sea captain who received the vast Rancho Nipomo in 1837 under Mexican rule. During the rancho era, it became an important stop on the route between Monterey and Los Angeles, welcoming travelers such as Henry Tefft and John C. Frémont. It also served as a key exchange point on California’s first official mail route between those centers. Today, the site interprets Rancho Era history and is recognized on the National Register of Historic Places, while Rancho Nipomo is a California Historical Landmark.