Second Presbyterian Church was founded in 1863 on land transferred by the First Church, with the chapel and manse resting on that property. The chapel had been built in 1847 as Oxford Furnace's first place of worship, a missionary church of First Presbyterian Church of Oxford, now known as First Presbyterian Church of Oxford at Hazen, and it also served as Oxford's first community center and for a time the town's schoolhouse. The original stone chapel was destroyed by fire, and the existing brick church was erected on its foundation in 1866 on land deeded to Second Presbyterian Church by the Scranton family, proprietors of Oxford Furnace and among the congregation's founders. Rev. E. Clarke Cline became the first installed minister on January 31, 1866, after serving as Civil War chaplain for the 11th NJ Regiment. The manse was built in 1873 to house pastors and their families and today serves as offices for the church and community missions.