The Ladonia Presbyterian Church, U.S.A., originally organized in the mid-19th century, erected this structure between 1910 and 1912. The building contract was awarded to W.H. Markley of Commerce for $6,400. An excellent example of 20th century Mission Revival style adapted to an ecclesiastical mode, the structure exhibits fine detailing and proportions with a simplicity of form. The congregation was dissolved by 1976. The character-defining central parapet was reconstructed in 1997.