The Euhaw congregation constituted this church on 24 March 1832, naming it Coosawhatchie Baptist Church. In December 1845, the South Carolina Baptist Convention met here and unanimously voted to join the recently formed Southern Baptist Convention. In February 1865, General William Tecumseh Sherman's troops visited the church and etched "War of 18621 &62 & 63 & 64 Feb. 7th 1865 this is done by a Yankee Soldier," on the communion silver. On 19 November 1885, the congregation became Gillisonville Baptist Church. The 1845 church building, placed on the National Register of Historic Places in 1971, is a local interpretation of Greek Revival style architecture, with notable features including the slave gallery and box pews.