Catfish Lake South Wilderness is a federally designated wilderness area in the Croatan National Forest of eastern North Carolina. Established in 1984, it encompasses 8,491 acres of broad wetland and remains notably undeveloped. With no trails or campsites, it is difficult to move through, and its significance lies in that remoteness. The area preserves a large, pathless wetland landscape where access is challenging and the natural character has remained largely unmodified.